1. Overview of Aerobic Respiration
  • Aerobic respiration has four stages: Glycolysis (cytoplasm) → Transition/Link reaction (mitochondrial matrix) → Krebs cycle (matrix) → Electron transport chain / oxidative phosphorylation (inner mitochondrial membrane).

Stage

Location

Net Products (per glucose)

Glycolysis

Cytoplasm

2 Pyruvate, net 2 ATP, 2 NADH₂

Transition reaction

Mitochondrial matrix

2 Acetyl CoA, 2 CO₂, 2 NADH₂

Krebs cycle

Mitochondrial matrix

2 ATP, 6 NADH₂, 2 FADH₂, 4 CO₂

Electron transport chain

Inner mitochondrial membrane

~34 ATP, H₂O (O₂ is final acceptor)